Monday, 24 February 2020
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Opioid dependence found to permanently change brains of rats

Added: 23.02.2020 20:35 | 2 views | 0 comments

Approximately one-quarter of patients who are prescribed opioids for chronic pain misuse them, with five to 10 percent developing an opioid use disorder or addiction. In a new study, researchers found that opioid dependence produced permanent changes in the brains of rats.

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First treatment for pain using human stem cells a success

Added: 23.02.2020 20:35 | 3 views | 0 comments

Researchers have used human stem cells to make pain-killing neurons that provide lasting relief in mice, without side effects, in a single treatment. The next step is to perform extensive safety tests in rodents and pigs, and then move to human patients suffering chronic pain within the next five years.

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Our biological clock plays crucial role in healing from surgery

Added: 23.02.2020 20:35 | 3 views | 0 comments

If you have just had knee, shoulder or hip surgery, you may want to take anti-inflammatories in the morning or at noon, but not at night. A new study shows, for the first time, that circadian clock genes are involved in healing from surgery. Indeed, the researchers demonstrated that anti-inflammatory medications are most effective in promoting post-operative healing and recovery when taken during the active periods of our biological clocks.

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Focus on opioids and cannabis in chronic pain media coverage

Added: 23.02.2020 20:35 | 3 views | 0 comments

New Zealand media reports on chronic pain are focusing on treatments involving opioids and cannabis at the expense of best practice non-drug treatments, researchers have found.

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'Swiss cheese' bones could be cause of unexplained low back pain

Added: 23.02.2020 20:35 | 4 views | 0 comments

In experiments with genetically engineered and old mice, researchers say they have added to evidence that the vast majority of low back pain in people may be rooted in an overgrowth of pain-sensing nerves into spinal cartilaginous tissue.

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New treatment for lupus

Added: 23.02.2020 20:35 | 3 views | 0 comments

Researchers offer the first real hope for the treatment of lupus, a disease which affects 1.5 million people in the US and more than 5 million globally, 90% women and for which there is no cure.

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Paper-based test could diagnose Lyme disease at early stages

Added: 23.02.2020 20:35 | 2 views | 0 comments

After a day hiking in the forest, the last thing a person wants to discover is a tick burrowing into their skin. Days after plucking off the bloodsucking insect, the hiker might develop a rash resembling a bull's-eye, a tell-tale sign of Lyme disease. Yet not everybody who contracts Lyme disease gets the rash. Now, researchers have devised a blood test that quickly and sensitively diagnoses the disease at early stages.

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Future painkillers: Activation of opioid receptor uncovered

Added: 23.02.2020 20:35 | 2 views | 0 comments

Researchers have uncovered the binding mechanism of an important pain receptor. The results facilitate the development of new active substances. The opioids used today to treat severe pain can be addictive and sometimes have life-threatening side effects.

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Cannabis reduces headache and migraine pain by nearly half

Added: 23.02.2020 20:35 | 3 views | 0 comments

Inhaled cannabis reduces self-reported headache severity by 47.3% and migraine severity by 49.6%, according to a recent study. The study also found no evidence that cannabis caused 'overuse headache,' a pitfall of more conventional treatments. The researchers did see patients using larger doses of cannabis over time, indicating they may be developing tolerance to the drug.

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Fighting opioids with an unlikely supplemental painkiller: Anti-itch medicine

Added: 23.02.2020 20:35 | 3 views | 0 comments

Researchers are investigating whether an anti-itch medication that targets a specific part of our nerve cells can make morphine -- which targets a different part--more effective. The findings suggest it can.

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