A genetic variant that protects the heart against cardiovascular disease has been discovered. The cardioprotective variant was found in an isolated Greek population, who are known to live long and healthy lives despite having a diet rich in animal fat.
Analysis of data from older adults who participated in a clinical trial showed no benefit of a statin for all-cause mortality or coronary heart disease events when a statin was started for primary prevention in older adults with hypertension and moderately high cholesterol, according to a new.
Studying how our bodies metabolize lipids such as fatty acids, triglycerides, and cholesterol can teach us about cardiovascular disease, diabetes, and other health problems, as well as reveal basic cellular functions. But the process of studying what happens to lipids after being consumed has been both technologically difficult and expensive to accomplish until now.
Exosomes isolated from very obese patients behave very differently than those derived from lean patients and may be key players in heightening youths' likelihood of developing atherosclerosis -- which, in turn, places them at higher risk for suffering heart disease and stroke as adults.
When patients were unaware they were taking statins there was no reported increase in muscle-related symptoms. But, when patients knew they were taking a statin, they were more likely to report symptoms, a finding consistent with the nocebo effect.
Cardiovascular risk factors such as high blood pressure, cholesterol and smoking have long been associated with cognitive deficiencies in adults. A new study found the burden of cardiovascular risk factors from childhood and adolescence is associated with worse midlife cognition regardless of adulthood exposure.
Vitamin A is an essential nutrient that the human body needs to function properly. But new research suggests that normal levels of vitamin A within a high-fat diet can negatively affect expression of liver genes associated with glucose and fat metabolism.
Fewer people could be recommended for primary prevention statin therapy, including many younger adults with high long-term cardiovascular disease risk, if physicians adhere to the 2016 US Preventive Services Task Force (USPSTF) recommendations for statin therapy compared with the 2013 American College of Cardiology/American Heart Association guidelines, according to a study.
Traffic-related air pollution may increase risk of developing cardiovascular diseases through its effects on high-density lipoprotein (HDL), also known as 'good' cholesterol. US middle-aged and older adults living in areas with high levels of traffic-related air pollution tended to have lower levels of good cholesterol. Changes in HDL levels were observed after brief and medium-length exposures to air pollution.
Cardiac glycosides reduce a precursor of LDL cholesterol in a drug screen of statin-resistant hypercholesterolemia, new research concludes. A large meta-analysis of medical records revealed that patients taking glycosides for heart failure had reductions in LDL cholesterol similar to patients taking statins. Cardiac glycosides are a potential treatment for patients with high cholesterol who don't respond to statins.