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|Cancer comparison across species highlights new drug targets|
Added: 23.05.2019 2:20 | 3 views | 0 comments
Cancer genes in mucosal melanoma, a rare and poorly understood subtype of melanoma, have been compared in humans, dogs and horses for the first time. Researchers sequenced the genomes of the same cancer across different species to pinpoint key cancer genes. The results give insights into how cancer evolves across the tree of life and could guide the development of new therapies.
|Unraveling the genetic causes of skin cancer|
Added: 23.05.2019 2:20 | 4 views | 0 comments
Medical researchers are helping to identify the genetic factors that lead to squamous cell carcinoma. In a new article, they show how the interaction between a cell signaling pathway called MET and a gene, Tpl2, contributes to skin cancer progression.
|Molecule discovery holds promise for gene therapies for psoriasis|
Added: 23.05.2019 2:20 | 0 views | 0 comments
Scientists have discovered a protein that could hold the key to novel gene therapies for skin problems including psoriasis - a common, chronic skin disease that affects over 100 million people worldwide.
|New role in spatial chromosome organization identified for often mutated cancer protein|
Added: 23.05.2019 1:18 | 12 views | 0 comments
New research sheds light on the function of the ARID1A protein, encoded by a gene that is among the most frequently mutated across human cancers.
|Massive sequencing study links rare DNA alterations to type 2 diabetes|
Added: 23.05.2019 1:18 | 7 views | 0 comments
An international consortium of scientists has analyzed protein-coding genes from nearly 46,000 people, linking rare DNA alterations to type 2 diabetes. From this large cohort the researchers identified four genes with rare variants that affect diabetes risk. The data suggests that hundreds more genes will likely be identified in the future.
|Experimental noninvasive tool monitors effectiveness of stem cell transplantation|
Added: 23.05.2019 1:18 | 6 views | 0 comments
Other than clinical observations, the stem cell field lacks a repeatable, time-sensitive, noninvasive tool to assess the effectiveness of transplanted cells in the targeted organ. Researchers analyzed biomarkers secreted from transplanted human stem cells in the recipient blood of a rodent model of heart attack. Analysis of the blood test showed responding cells had changed their gene expression, behavior and secretions, suggesting this liquid biopsy could provide a window into stem cell activity and effectiveness.
|ATP roundup: Wawrinka among top seeds upset in Geneva|
Added: 22.05.2019 23:13 | 13 views | 0 comments
Two-time winner and local favorite Stan Wawrinka was ousted in the Round of 16 at the Banque Eric Sturdza Geneva Open in Switzerland on Wednesday, as Bosnia's Damir Dzumhur rallied past him 3-6, 6-3, 6-4.
|Scientists discover novel genes responsible for regulating muscle cells|
Added: 22.05.2019 20:31 | 10 views | 0 comments
Scientists have uncovered a unique set of genes that play a role in muscle cellular gene expression and differentiation which could lead to new therapeutic targets to prevent the spread of muscle cancer.
|New Genoa bridge expected to be completed by April 2020|
Added: 22.05.2019 18:16 | 13 views | 0 comments
Rebuilding work on a bridge that collapsed in the Italian city of Genoa last year killing 43 people is expected to be completed by next April despite demolition works running late, the special commissioner for the reconstruction said on Wednesday.
|Games Have a Grind Problem|
Added: 22.05.2019 17:32 | 1 views | 0 comments
Regardless of whether or not it suits a genre, developers and publishers alike are putting it in there as a tool to keep fans playing and even bore them into engaging with their MTX. As Mortal Kombat 11 has shown, even a titan of the fighter-genre isnt immune to their appeal. Its good that fans called them out on it this time, but we cant expect them to exercise some restraint until we do so ourselves. If you dont want to see even more ridiculous grind in games it doesnt belong in, then please dont buy the MTX theyre pushing. Its the only way theyll learn and the only way we can end unnecessary grind.
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