Researchers have discovered a hyperactive cell signal that contributes to tumor growth in primary effusion lymphoma, an aggressive type of non-Hodgkin lymphoma caused by infection with the Kaposi's sarcoma-associated herpesvirus (human herpesvirus-8). They've developed an experimental therapeutic, UNC3810A, to block the signal and slow tumor growth.
Scientists have identified 12 distinct types of gene-pair interactions in which varying levels of expression in the two genes correlated with cancer patient survival. The results suggest that genes involved in such paired interactions could provide new targets for cancer therapy.
Valerie Harper's husband, Tony Cacciotti, recently revealed that doctors have recommended he put the "Mary Tyler Moore Show" star -- who has been battling cancer -- in hospice care.
Recent research has shown that a drug known as MI-2 can kill cells that cause a fatal brain cancer. But only now have scientists been able to explain how the compound works: by targeting cholesterol production in tumors.
Researchers have revealed the full structure of human ACLY, a building block of metabolism over-expressed in several types of cancers. Their discovery could be a major step in developing molecular targeted therapies for patients.
A research team has unraveled the three-dimensional structure and molecular mechanism of ATP citrate lyase (ACLY). This is a central metabolic enzyme -- a protein that accelerates chemical reactions -- important for the production of fatty acids and cholesterol in the human liver. The reported findings could help targeting ACLY in cancer and metabolic diseases such as atherosclerosis.
“Jeopardy!” host Alex Trebek celebrated his 79th birthday with friends, family and well-wishers amid his ongoing battle with stage 4 pancreatic cancer.
Top Gun’s Val Kilmer delivered a speech at the United Nations Headquarters in New York City over the weekend after taking a step out of the spotlight for several years due to his battle with throat cancer.
