Over the past year, at least seven children have died from diseases including influenza while being detained by the US Department of Homeland Security's Customs and Border Protection (CBP) agency. Infectious disease experts have called for protections like influenza vaccinations to prevent serious outbreaks.
First identified in 2012, the MERS-coronavirus is capable of causing severe pneumonia. There are no effective treatments for MERS. Researchers have now identified a cellular recycling process known as autophagy as a potential target in the fight against MERS. Autophagy-inducing substances - including licensed drugs - were shown to be capable of reducing the viral replication rate.
New research has highlighted the role domesticated animals -- both pets and livestock -- play in the spread of viruses among humans and wildlife. The study has revealed the patterns of how viruses are shared differs between the two major groups of RNA and DNA viruses.
According to a Feb. 13 report from the World Health Organization, the Wuhan coronavirus has stricken more than 46,000 people and has caused over 1,300 deaths since the first cases in Wuhan, China, in December 2019. Now, researchers have designed compounds that block the replication of similar coronaviruses, as well as other disease-causing viruses, in the lab. The compounds have not yet been tested in people.
Researchers report the biological effects of influenza protein NS1 binding to RIG-I -- the binding directly quiets the alarm that activates the cellular innate immunity defense against the infection. This is a newly described way for flu to antagonize the host cellular antiviral response.
Emerging viral infections -- from bird flu to Ebola to Zika infections -- pose major threats to global public health, and understanding their origins can help investigators design defensive strategies against future outbreaks. A new study provides important insights on the potential origins of the most recent outbreak of viral pneumonia in China, which started in the middle of December and now is spreading to Hong Kong, Singapore, Thailand, and Japan.
A new study puts researchers within closer reach of vaccines that can protect infants against infections by overcoming a mother's antibodies, which are known to shut down immune defenses initiated by conventional vaccines. That hurdle largely explains why vaccinations for infectious diseases like influenza and measles not given until six to 12 months of age.
New viruses which cause diseases often come from animals. Well-known examples of this are the Zika virus transmitted by mosquitoes, bird flu viruses, as well as the MERS virus which is associated with camels. In order to identify new viral diseases quickly and prevent possible epidemics, scientists are targeting their search at viruses in animals. In a current study, they have now discovered hundreds of novel viruses in insects.
A novel nanoparticle vaccine that combines two major influenza proteins is effective in providing broad, long-lasting protection against influenza virus in mice, showing promise as a universal flu vaccine, according to a new study.
Physicians and scientists have found that injecting tumors with influenza vaccines, including some FDA-approved seasonal flu shots, turns cold tumors to hot, a discovery that could lead to an immunotherapy to treat cancer.
Analyzing public health records from Arizona to study how different strains of the flu virus affect people of different ages, researchers found that the first strain we encounter during childhood sets the course of how our immune system responds to exposures later in life.
An experimental vaccine against the Zika virus reduced the amount of virus in pregnant rhesus macaques and improved fetal outcomes. The work could help support development and approval of an experimental Zika DNA vaccine currently in early stage trials in humans.
Researchers showed, for the first time, that a single, higher dose of vaccination to a pregnant mouse safely protects both her and her fetus from the Zika virus. The researchers found that a single, less potent dose was not enough to protect the fetus.
Normally, bird flu viruses do not spread easily from person to person. But if this does happen, it could trigger a pandemic. Researchers have now explained what makes the leap from animals to humans less likely.