Researchers have developed new antimicrobial technology for air filters which can in seconds kill bacteria, fungi and viruses including SARS-CoV-2 -- providing a potential solution to prevent the spread of airborne infections.
The world's largest study of the genetics of critical COVID-19, involving more than 57,000 people, has revealed fresh details about some of the biological mechanisms behind the severe form of the disease.
Disease and health are the result of a complex interaction between humans and their pathogens. Genetic factors that partly determine host defenses sometimes differ significantly between people and populations. More genetic and immunological research in non-European populations will provide a better and more complete picture of how the human immune system works.
A study found people who cycled on a stationary bike or took a brisk walk for an hour-and-a-half after getting a flu shot or COVID-19 jab produced more antibodies in the following four weeks compared to participants who sat or continued with their daily routine post-immunization.
Scientists who have developed an inhaled form of COVID vaccine have confirmed it can provide broad, long-lasting protection against the original strain of SARS-CoV-2 and variants of concern. The research reveals the immune mechanisms and significant benefits of vaccines being delivered directly into the respiratory tract, rather than by traditional injection.
Researchers have found that children who receive years of season-specific flu vaccines develop antibodies that also provide broader protection against new strains, including those capable of causing pandemics.
Dozens of mutations in the spike protein of the Omicron variant help it to evade all four of the classes of antibodies that can target SARS-CoV-2, according to a new study. This includes antibodies generated by the immune systems of vaccinated or previously infected people, as well as most of the monoclonal antibody treatments that have been developed.
An influenza vaccine administered through the nose and constructed with nanoparticles that enhance immune response offers strong protection against different influenza virus strains, according to researchers.
Researchers designed a new nanoparticle adjuvant that may be more potent than others now in use. Studies in mice showed it significantly improved antibody production following vaccination against HIV, diphtheria and influenza.
Vaccines are effective in decreasing hospitalization and deaths from COVID-19 infection but the emergence of viral variants of concern may diminish their efficacy. A new study suggests that COVID-19 Delta variant may be more successful at evading the protective response of vaccines.
In a new study, researchers report a new candidate ribonucleoside analog, 4'-fluorouridine (4'-FlU), that has potent antiviral activity against SARS-CoV-2, RSV and other respiratory RNA viruses in cell culture, human organoids and different animal models when administered orally once-daily.
Nanoengineers have developed a new and potentially more effective way to deliver messenger RNA (mRNA) into cells. Their approach involves packing mRNA inside nanoparticles that mimic the flu virus -- a naturally efficient vehicle for delivering genetic material such as RNA inside cells.
A new statistical analysis supports beliefs that COVID-19 became more lethal in the U.K. in late 2020, while also suggesting that multiple factors -- not just the alpha variant of the virus that causes COVID-19 -- were to blame.
Accurately assessing the exposure of a population to a particular virus is difficult because the tools for doing so do not account for the fact that many viruses comprise multiple circulating strains, or the fact that people can be vaccinated or naturally immune, among other factors. Using influenza as a model, researchers have developed a new technique that overcomes many of these roadblocks, and they say the tool may be useful for better assessments of exposure to a variety of viruses, including the ones that cause COVID-19 and pneumonia.
New research provides evidence that host immunity drives evolution of the dengue virus. The research analyzes two decades of genetic variation from Thailand alongside population-level measures of infection and immunity.
More than half of U.S. adults are carriers of HSV1 (herpes simplex virus type 1) which hibernates in the peripheral nervous system and can never be eradicated. A new study has uncovered herpes' sneaky strategy for infecting the nervous system, opening a door to long-needed vaccine development for both HSV1 and its close sibling HSV2.
New research suggests there may someday be a role for ibuprofen in providing older adults with lasting immunity against RSV, a virus commonly associated with infants and young kids that also rivals the flu as a dangerous wintertime infection for the elderly.