E-cigarette vapor boosts the production of inflammatory chemicals and disables key protective cells in the lung that keep the air spaces clear of potentially harmful particles, reveals a small experimental study.

Chronic obstructive pulmonary disease (COPD) is a disease of accelerated lung aging, but the mechanism remains unclear. Researchers studied the aging-like phenotype and its underlying mechanisms in a COPD mouse model. Double deletion of tetraspanins CD9 and CD81 in epithelial cells downregulated expression of the protein SIRT. As SIRT1 is a key molecule that protects against various lifestyle-related diseases and aging, these tetraspanins may serve as novel therapeutic targets for COPD and aging.

Dominic Cummings, special advisor to British prime minister Boris Johnson and a zealous advocate of Brexit, benefitted from EU agriculture subsidies via a farm that he co-owned with his relatives, British newspaper The Observer reported on Sunday. The farm in Durham, northern England, received about €250,000 of EU funds over 20 years, records showed. The news exposed Cummings' "sheer hypocrisy", a spokeswoman for the British opposition Liberal Party said.

About 800,000 British people have spent €4.3bn stockpiling food, drinks, and medicine in case a no-deal Brexit on 31 October causes supply problems, according to data from British financial firm Premium Credit. "The British would be the big losers," in a hard Brexit, outgoing European Commission chief Jean-Claude Juncker also said in Tiroler Tageszeitung, an Austrian newspaper, on Saturday. "We [the EU] are well prepared [for no-deal Brexit]," he added.

The EU needs to properly classify which economic activities help the environment to help direct public funding and private investment toward climate-friendly sectors, EU financial services commissioner Valdis Dombrovskis has told the Financial Times newspaper. "In this way you avoid greenwashing, you provide clarity," he said. The European Commission proposed a new classification scheme last year, but capitals are wary of giving Brussels more power on dividing up joint funds.

In a recent interview to promote Pedro Almodóvar's “Pain and Glory,” the Spanish actor said he wouldn’t be alive today if not for a drag performer.

Drejka fatally shot Markeis McGlockton, 28, outside of a Clearwater convenience store on July 19, 2018.

The commanders of a rescue ship with 107 migrants aboard declined to leave Italian waters on Monday, turning down an option to take them to Spain and suggesting that Italy's Coast Guard should take them there instead.

An administrative judge had earlier recommended that Pantaleo be terminated. Garner's death, which sparked national protests, occurred on July 17, 2014.

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