How does a normal cell turn into a deadly cancer? Seeking an answer to this Question researchers examined the tumor genomes of nearly 300 prostate cancer patients. Their findings describe the ways in which changes in the prostate cells' genetic information pave the way for cancer development. Using a newly developed computer model, it is now possible to predict the course of the disease in individual patients.
A report describes a new assay to assess copy number alterations that is cheaper, faster, reproducible, and requires less tissue than other diagnostic techniques and has the potential to significantly enhance prostate cancer evaluation.