Diseases such as multiple sclerosis are characterized by damage to the 'myelin sheath', a protective covering wrapped around nerve cells akin to insulation around an electrical wire. Researchers have discovered how the body initiates repair mechanisms which will limit the extent of any damage to this sheath. Their findings may provide a basis for the development of new drugs to treat multiple sclerosis.
A research team presents a noninvasive light-sensitive photoactivatable recombinase suitable for genetic manipulation in vivo. The highly light-sensitive property of photoactivatable Flp recombinase will be ideal for controlling genetic manipulation in deep mouse brain regions by illumination with a noninvasive light-emitting diode. This easy-to-use optogenetic module will provide a side-effect free and expandable genetic manipulation tool for neuroscience research.
Researchers have tested the sounds made by six different acoustic guitars in a study addressing the effects of the type of wood used in their construction. Some of the woods used for guitar backs are revered by guitar players for their acoustic qualities, and are claimed to be tonally superior to other woods. Unfortunately many of these woods are expensive, rare, and from unsustainable sources.
Current hygiene measures against aggressive germs could sometimes be counterproductive, according to a group of researchers. They propose to examine the role diversity of microorganisms plays in our domestic environment tensively. The findings could challenge existing strategies for fighting infectious diseases and resistant germs.
Doctors in intensive care units face a continual dilemma: Every blood test they order could yield critical information, but also adds costs and risks for patients. To address this challenge, researchers are developing a computational approach to help clinicians more effectively monitor patients' conditions and make decisions about the best opportunities to order lab tests for specific patients.
What happens to sex pheromones as new species emerge? New research studies sex pheromones in the fission yeast Schizosaccharomyces pombe, revealing an 'asymmetric' pheromone recognition system in which one pheromone operates extremely stringently whereas the other pheromone is free to undergo a certain degree of diversification, perhaps leading to a first step towards speciation.
Using multiple genomic sequencing tests, TGen identified a specific non-polio enterovirus -- EV-D68 -- among at least four children, according to a new study. The finding is significant because AFM cases are continuing to increase and there has been no official recognition that this disease is being caused by EV-D68, which limits the research community's ability to develop preventative measures, such as new vaccines.
The DNA replication process, which takes place every time a cell divides, also triggers repair of DNA damage, researchers have described in a new study. Scientists have studied extracts from frog eggs, whose proteins are very similar to those of human cells. The researchers hope the new research results can be used to develop more effective treatments for cancer in the long run.
Corals know how to attract good company. New research finds that corals emit an enticing fluorescent green light that attracts the mobile microalgae, known as Symbiodinium, that are critical to the establishment of a healthy partnership.
Keeping track of who wears which costume, the location of soccer cleats and what is in the pantry are all examples invisible labor, or the mental and emotional effort required of mothers as they raise children and manage households. Researchers quantified the prevalence and impact of invisible labor. Feeling solely responsible for the household and children strained mothers' well-being and decreased satisfaction with their lives and partnerships.
The faint, ephemeral glow emanating from the planetary nebula ESO 577-24 persists for only a short time -- around 10,000 years, a blink of an eye in astronomical terms. ESO's Very Large Telescope captured this shell of glowing ionized gas -- the last breath of the dying star whose simmering remains are visible at the heart of this image. As the gaseous shell of this planetary nebula expands and grows dimmer, it will slowly disappear from sight.