A tiny drug-delivery system has been invented that can identify cancer cell types in the brain through 'virtual biopsies' and then attack the molecular structure of the disease. The results could be used to deliver nano-scale drugs that can distinguish and fight tumor cells in the brain without resorting to surgery, the authors say.
Studying zebrafish, investigators have discovered a new source for cells that can develop into coronary vessels and have identified the signaling protein, a chemokine called CXCL12, which guides this process.
In a small study in Chile that included patients with gallbladder cancer, exposure to aflatoxin (a toxin produced by mold) was associated with an increased risk of gallbladder cancer. In Chile, gallbladder cancer is a leading cause of cancer death in women. Exposure to aflatoxin, a liver carcinogen, is associated with gallbladder cancer in primates.
We live in fear of 'superbugs': infectious bacteria that don't respond to treatment by antibiotics, and can turn a routine hospital stay into a nightmare. Now, researchers have designed a diagnostic chip to reduce testing time of antibiotics from days to one hour, allowing doctors to pick the right antibiotic the first time.
A unique, high performance foam has been developed that can be used to make safer athletic gear and medical equipment, among other things. The developers anticipate an immediate benefit to the medical device and protective equipment industries while the collaborative project for the development of the new prosthetic sock is underway.
Maxing out the inherently stressed nature of treatment-resistant breast cancer cells thwarts their adaptive ability to evolve genetic workarounds to treatment, according to a study. Looking at tumor progression as essentially an evolutionary process, researchers highlight the feasibility of maximizing cell stress by inhibiting adaptive pathways to cause cell death.
Astronomers have found that the black holes located at the cores of galaxies launch fountains of charged particles, which can stir up gas throughout the galaxy and temporarily interrupt star formation. But unless something intervenes, the gas will eventually cool and start forming stars again.
In an analysis that included more than 70,000 participants from 13 studies, subclinical hyperthyroidism was associated with an increased risk for hip and other fractures including spine. Subclinical hyperthyroidism is a low serum thyroid-stimulating hormone concentration in a person without clinical symptoms and normal thyroid hormone concentrations on blood tests.
Individually rare but collectively common intermediate-size copy number variations may be negatively associated with educational attainment, according to a study. Copy number variations (CNVs) are regions of the genome that differ in the number of segments of DNA.
Researchers have now shown that they can assemble DNA nanostructures in a solvent containing no water. They also discovered that adding a small amount of water to their solvent increases the assembly rate and provides a new means for controlling the process. The solvent may also facilitate the production of more complex structures by reducing the problem of DNA becoming trapped in unintended structures.
The importance of the umbilical cord for both the fetus and for newborn infants was demonstrated by researchers several years ago, in a study that received great international acclaim. In a follow-up study, the researchers have now been able to show an association between delayed cord clamping (DCC) and children's fine motor skills at the age of four years, especially in boys.
Despite previous findings suggesting a link between soy intake and decreased asthma severity, a new placebo-controlled study shows soy supplements do not improve lung function for patients with asthma. The paper highlights the importance of focusing on overall health -- not just one food -- to manage disease and the importance of performing well-designed studies.
Maps show us the way and identify major landmarks – rivers, towns, roads and hills. For centuries, they also offered a perspective on how societies viewed themselves in comparison to the rest of the world. New research looks at maps from the medieval and early-modern Muslim world.
Analogical ability -- the ability to see common relations between objects, events or ideas -- is a key skill that underlies human intelligence and differentiates humans from other apes. While there is considerable evidence that preschoolers can learn abstract relations, it remains an open question whether infants can as well. In a new study, researchers found infants are capable of learning the abstract relations of same and different after only a few examples.
Portable electronics -- typically made of non-renewable, non-biodegradable and potentially toxic materials -- are discarded at an alarming rate in consumers' pursuit of the next best electronic gadget. In an effort to alleviate the environmental burden of electronic devices, scientists have develop a surprising solution: a semiconductor chip made almost entirely of wood.
Spouses of patients receiving hospice for three or more days more frequently reported reduced depression symptoms, compared to surviving spouses of patients who did not receive hospice, a new report concludes.
There’s more than one way to gain a sense of control. The traditional view of a life in control is one in which an individual has taken actions to ensure success in both the near and long terms. “Secondary control,” has been given short shrift in both the scientific literature and the attitudes of Western societies. Secondary control can be described as a mindset in which one accepts and adapts to the fact that much of life can’t be bent to human will.