Tuesday, 02 March 2021
Advanced imaging technology captures translation of the maternal genome

Added: 23.02.2021 0:18 | 25 views | 0 comments

Source: www.slideshare.net
Source: www.slideshare.net

Researchers have captured ribosomes translating messenger RNA expressed from the maternally inherited mitochondrial genome. Utilizing the latest advances in cryo-electron microscopy, the group discovered a novel mechanism that mitochondrial ribosomes use for the synthesis and delivery of newly made proteins to prevent premature misfolding. Disruptions to protein folding can lead to devastating human diseases.

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