In some cases, immune cells in the lungs can contribute to worsening a virus attack. In a new study, researchers describe how different kinds of immune cells, called macrophages, develop in the lungs and which of them may be behind severe lung diseases. The study may contribute to future treatments for COVID-19, among other diseases.
Scientists show effectiveness of carrot-based Japanese herbal medicine called 'Ninjin'yoeito' in improving muscle atrophy in the hind legs of mice exposed to cigarette smoke, positioning the medicine as a potential treatment for sarcopenia frailty-related complications with chronic obstructive pulmonary disease (COPD).
Construction workers in Alberta, Canada who work with hazardous insulation materials are much more likely to be affected by repeated chest infections and chronic obstructive pulmonary disease (COPD), according to new research.
For young people with cystic fibrosis, lung infection with Staphylococcus aureus, MRSA, is common and is treated with antibiotics in the hope that this will prevent a decline in lung function. However there has recently been debate over the role S. aureus plays in CF lung disease. Researchers have used a new model of CF lungs which could be used to make better decisions about future use of antibiotics.
In a preclinical study, researchers identified and characterized 18 new compounds (agonists) that activate bitter taste receptor subtype TAS2R5 to promote relaxation of human airway smooth muscle cells. The cross-disciplinary team found 1,10 phenanthroline-5,6-dione (T5-8 for short) was 1,000 times more potent than some of the other bronchodilator agonists tested, and it demonstrated marked effectiveness in human airway smooth muscle cells grown in the laboratory.
Early-life events, such as the exposure to air pollutants, increases the risk of chronic lung disease in young adulthood, according to new results. The studies add to the growing evidence that chronic lung disease in adulthood can be traced back to childhood.
New research findings contradict statements linking wearing face masks to carbon dioxide poisoning by trapping carbon dioxide. During the COVID-19 pandemic the wearing of face masks has become a highly political issue with some individuals falsely claiming that wearing face masks may be putting people's health at risk.
Cannabinoids, a class of prescription pills that contain synthetically-made chemicals found in marijuana, are associated with a 64 per cent increase in death among older adults with chronic obstructive pulmonary disease (COPD), according to the first published data on the impact of cannabinoids on the respiratory health of individuals with the lung disease.
Vapers, smokers, and non-smokers with chronic conditions are all at higher risk for COVID-19. The scientific explanation behind this is complex and not yet certain -- but it may boil down to an enzyme known as ACE2, that lives on the surface of many cells in the lungs and serves as the entry point for the coronavirus.
People who had bronchitis at least once before the age of seven are more likely to develop lung problems in later life, according to new research. However, the lung diseases they suffer from by the age of 53 were usually asthma and pneumonia rather than chronic bronchitis.
Medical researchers have released new clinical practice guidelines to help advise clinicians on the optimal management of patients with chronic obstructive pulmonary disease (COPD) and chronic hypercapnia. Hypercapnia is the buildup of carbon dioxide in the bloodstream.
New insights into the molecular mechanisms driving mucus viscosity were have been discovered. A discovery about how mucus thickness is regulated could help to improve airway-clearing treatment options for people with chronic respiratory conditions such as asthma, cystic fibrosis and chronic obstructive pulmonary disease (COPD).
Two stem cell researchers have found an abundance of abnormal stem cells in the lungs of patients who suffer from Chronic Obstructive Pulmonary Disease (COPD), a leading cause of death worldwide. The team, who used single cell cloning of lung stem cells to make their discovery, is now targeting the cells for new therapeutics.
A new study shows that lung stem cell secretions -- specifically exosomes and secretomes -- delivered via nebulizer, can help repair lung injuries due to multiple types of pulmonary fibrosis in mice and rats.