The first results from a functional genetic catalogue of the laboratory mouse has been shared with the biomedical research community, revealing new insights into a range of rare diseases and the possibility of accelerating development of new treatments and precision medicine.
One of the big challenges in the neuroscience field is to understand how connections and communications trigger our behavior. Researchers have now developed a tool to identify and control neurons. The new technique, called Calcium and Light-Induced Gene Handling Toolkit or 'Cal-Light,' allows researchers to observe and manipulate the neural activities underlying behavior with never-before-seen specificity, hopefully allowing researchers to identify causality between neuronal activity and behavior.
And to think it was all right there in her garage. A load of boxes pulled from a biologist's home yielded a veritable treasure trove for researchers studying the impact of climate change on coastal biodiversity in California.
Scientists show how some pathogenic bacteria -- such as the mycobacteria that cause tuberculosis -- use a previously unknown mechanism to coordinate their division. The discovery could help develop new ways to fight them.
Researchers have discovered a new, yet simple, way to increase drought tolerance in a wide range of plants. The study reports a newly discovered biological pathway that is activated in times of drought. By working out the details of this pathway, scientists were able to induce greater tolerance for drought-like conditions simply by growing plants in vinegar.
The peanut and its kin -- legumes -- have not one, but two ways to make the amino acid tyrosine. That might seem small, but why this plant family has a unique way to make such an important chemical building block is a mystery that extends back to the 1960s.
Discovering the function of a gene requires cloning a DNA sequence and expressing it. Until now, this was performed on a one-gene-at-a-time basis, causing a bottleneck. Scientists have invented a technology to clone thousands of genes simultaneously and create massive libraries of proteins from DNA samples, potentially ushering in a new era of functional genomics.
Most organisms share the biosynthetic pathways for making crucial nutrients because it is is dangerous to tinker with them. But now a collaborative team of scientists has caught plants in the process of altering where and how cells make an essential amino acid.
Just as people endlessly calculate how to upsize or downsize, bacteria continually adjust their volume (their stuff) to fit inside their membrane (their space). But what limits their expansion? The answer will surprise you.
During her study on fossil insects at China's Capitol Normal University, a student visited the Smithsonian National Museum of Natural History, USA, carrying two unidentified wasp specimens that were exceptionally well-preserved and 100 million years old. Close examination revealed that both were species new to science. Furthermore, one of them was found to belong to a genus of modern wasps.
New research results show how active transport of potassium can be achieved by a membrane protein complex that has roots in both ion pump and ion channel super-families. The results shed new light on what define channels and pumps.
Scientists have called for action to a serious lack of data on the worldwide distribution of disease-causing organisms. Without this knowledge, predicting where and when the next disease outbreak will emerge is hardly possible. Macroecologists hold the expertise to create the needed data network and close the knowledge gaps.